(E)	1.	下列那一類風濕免疫疾病的遺傳機率最高？
		A.	全身性紅斑狼瘡
		B.	類風濕性關節炎
		C.	修格連氏症候群(Sjogren's syndrome)
		D.	全身性硬皮症
		E.	僵直性脊椎炎
(B)	2.	退化性關節炎(Osteoarthritis)甚少侵犯的關節為
		A.	Distal interphalangeal joints
		B.	Wrist joint
		C.	Knee joint
		D.	Hip joint
		E.	Spine
(A)	3.	下列先天性免疫不全症(primary immunodeficiencies)中，主要以抗體不足或缺乏(antibody deficiency)為特徵之疾病是那一種？
		A.	Common variable immunodeficiency
		B.	Adenosine deaminase deficiency
		C.	Chronic granulomatous disease
		D.	Severe combined immunodeficiency
		E.	Di George's syndrome
(B)	4.	每一類風濕病常有典型特殊的X光變化；請問下列配對，何者為誤？
		A.	Rheumatoid arthritis --- marginal erosion
		B.	Osteoarthritis --- osteoporosis
		C.	Psoriatic arthritis --- " Pencil - in - cup " appearance
		D.	Ankylosing spondylitis --- syndesmophyte
		E.	Pseudogout --- chondrocalcinosis
(A)	5.	膠原疾病(collagen disease)常侵犯腎臟造成嚴重後果。請問最易侵犯腎小管(renal tubule)內造成腎小管性酸血症(renal tubular acidosis)之疾病是
		A.	修格連氏症(Sjogren's syndrome)
		B.	全身性紅斑狼瘡
		C.	皮肌炎(dermatomyositis)
		D.	硬皮症(scleroderma)
		E.	類風濕性關節炎
(B)	6.	下列關於血管炎與其臨床特徵之配對中，何者為誤？
		A.	Temporal arteritis --- high ESR
		B.	Henoch-Schonlein Purpura --- IgG immune complexes
		C.	Wegener's granulomatosis --- anti-neutrophil cytoplasmic antibody
		D.	Polyarteritis nodosa - Hepatitis B antigenemia
		E.	Churg - Strauss disease - eosinophilia
(B)	7.	下列關於硬皮症(scleroderma)在心臟血管系統所造成的異常之描述，那一項是不正確的？
		A.	可發生肺高壓而導致右心衰竭
		B.	可發生心絞痛，而且冠狀動脈攝影檢查常可見狹窄異常
		C.	雷諾氏現象(Raynaud's phenomenon)可發生在耳或鼻處
		D.	可發生心包膜積水(Pericardial effusion)
		E.	可發生心肌纖維化而導致左心衰竭
(D)	8.	肌腱(tendon)或韌帶(ligament)附著於骨(bone)之處稱之為enthesis。下列那一類風濕病是以enthesis發炎(enthesopathy)為其臨床最主要的特色？
		A.	痛風(gout)
		B.	退化性關節炎(osteoarthritis)
		C.	類風濕性關節炎(rheumatoid arthritis)
		D.	僵直性脊椎炎(ankylosing spondylitis)
		E.	敗血性關節炎(septic arthritis)
(A)	9.	被認為可以改變類風濕性關節炎病程的藥物(Disease-modifying anti-rheumatic drugs, DMARD)包括 1. anti-malarials 2. corticosteroid 3. indomethacin 4. sulfasalazine 5. D-penicillamine
		A.	1, 4, 5
		B.	2, 5
		C.	2, 3, 4
		D.	3, 4, 5
		E.	1, 2, 3
(C)	10.	可經由尿酸過度產生(urate overproduction)而造成高尿酸血症(hyperuricemia)之臨床疾病包括 1. lead intoxication 2. hemolytic anemia 3. diabetic ketoacidosis 4. lymphoma 5. psoriasis
		A.	1, 2, 3
		B.	2, 3, 5
		C.	2, 4, 5
		D.	3, 4
		E.	1, 4