| (C) | 1. |
一位25歲女性因為貧血、深色尿求診，血液相如下：血紅素9.5 g/dL，MCV 95fL，網狀紅血球7.8%，白血球及血小板無異樣，血清AST 85 U/L，ALT 30 U/L，bilirubin全量3.1 mg/dL，直接型0.8 mg/dL，LDH 1,560 U/L，小便潛血陽性，但沈澱物中無明顯白血球及紅血球，下列各項檢查中何者對診斷最不需要？
|
| A. | Flow cytometry for CD55, CD59 |
| B. | Coombs' test |
| C. | Osmotic fragility test |
| D. | Cold agglutinin |
| E. | G6PD |
| |
| (B) | 2. |
一位45歲男性，無其他全身性疾病，因為皮膚瘀青應診，但其他部位無出血現象。血液檢查顯示血紅素13.1 g/dL，白血球9,550/uL，血小板16,000/uL，骨髓檢查無特殊異常。下列何者為對此病人最適當的處置？
|
| A. | Glucocorticoid plus platelet concentrate transfusion |
| B. | Glucocorticoid alone |
| C. | Intravenous immunoglobulin plus platelet concentrate transfusion |
| D. | Intravenous immunoglobulin alone |
| E. | Glucocorticoid, intravenous immunoglobulin and platelet concentrate transfusion |
| |
| (C) | 3. |
下列容易引發栓塞之遺傳性缺陷中，何者在台灣最常見？
|
| A. | Antithrombin III deficiency |
| B. | Protein C deficiency |
| C. | Protein S deficiency |
| D. | FactorＶ Leiden mutation |
| E. | Prothrombin 20210A mutation |
| |
| (A) | 4. |
為預防發熱性非溶血性輸血反應(febrile nonhemolytic transfusion reaction)，在輸血前先給予何種處置？
|
| A. | Antipyretic agent |
| B. | Antihistamine |
| C. | Glucocorticoid |
| D. | Antibiotics |
| E. | Irradiation of blood cellular components |
| |
| (B) | 5. |
一位26歲女孩因經血過多應診，身體無其他異狀。血液檢查顯示血紅素10.2 g/dL，白血球5,850/uL，分類正常，血小板187,000/uL；出血時間稍長，PT正常，PTT延長。下列何者是此病人最可能的診斷？
|
| A. | Hemophilia |
| B. | von Willebrand disease |
| C. | Uremia |
| D. | Disseminated intravascular coagulation |
| E. | Hepatitis |
| |
| (E) | 6. |
下列各微生物感染及其相關之淋巴瘤對應中，何者是錯誤的？
|
| A. | Helicobacter pylori： gastric MALT lymphoma |
| B. | HTLV-1： adult T-cell leukemia/lymphoma |
| C. | Epstein-Barr virus： nasal NK/T cell lymphoma |
| D. | HIV： diffuse large B cell lymphoma |
| E. | Human herpes virus 8： Burkitt lymphoma |
| |
| (D) | 7. |
下列何種狀況最不可能造成erythrocytosis？
|
| A. | Chronic obstructive pulmonary disease |
| B. | Right-to-left shunts |
| C. | Penal cell carcinoma |
| D. | Hyperthyroidism |
| E. | Smoking |
| |
| (E) | 8. |
下列何者為不明原因之thrombotic thrombocytopenic purpura常見的變化？ (應選出全部答案)
1. Schistocytes
2. ADAMTS13 deficiency
3. High LDH level
4. Reticulocytosis
|
| A. | 1+3 |
| B. | 2+3 |
| C. | 1+2+3 |
| D. | 1+3+4 |
| E. | 1+2+3+4 |
| |
| (C) | 9. |
目前已知下列何種藥物可有效的治療多發性骨髓瘤？
1. Bevacizumab
2. Bortezomib
3. Thalidomide
4. Steroids (應選出全部答案)
|
| A. | 1+4 |
| B. | 2+3 |
| C. | 2+3+4 |
| D. | 1+2+3 |
| E. | 1+2+3+4 |
| |
| (C) | 10. |
缺鐵性貧血病人可出現下列種異常？
1. Microcytic anemia
2. Reticulocytosis
3. Mild thrombocytosis
4. Eosinophilia (應選出全部答案)
|
| A. | 1 |
| B. | 1, 2 |
| C. | 1, 3 |
| D. | 1, 2, 3 |
| E. | 1, 2, 3, 4 |
| |